题目: purine alkaloids from the South China Sea gorgonian Subergorgia suberosa. 

作者: Qi S. H., Zhang S., Huang H. 

刊物: Journal Natural Products , （IF= 2.843 ，III区）

刊号: 2008, 71(4): 716-718 

摘要: Four new purine alkaloids, namely, 6-(1′-purine-6′,8′-dionyl)suberosanone (1), 3,9-(2-imino-1-methyl-4-imidazolidinone-5-yl)isopropenylpurine-6,8-dione (2), 1-(3′-carbonylbutyl)purine-6,8-dione (3), and 9-(3′-carbonylbutyl)purine-6,8-dione (4), together with three known compounds, guanosine (5), thymidine (6), and adenosine (7), were isolated from the EtOH/CH2Cl2 extracts of the South China Sea gorgonian Subergorgia suberosa. The structures of 1–4 were determined on the basis of extensive spectroscopic analysis, including 1D and 2D NMR data. Compounds 1−4 all showed weak cytotoxicity toward human cancer cell lines MDA-MB-231 and A435.