题目: Culturable actinobacteria isolated from marine sponge Iotrochota sp. 

作者: Jiang S. M., Li X., Zhang L., Sun W., Dai S. K., Xie L. W., Liu Y. H., Jung J. H. 

刊物: Marine Biology , （IF=2.074，IV区）

刊号: 2008 , 153(5): 945-952. 

摘要: The study describes the diversity of actinobacteria isolated from the marine sponge lotrochota sp. collected in the South China Sea. Species and natural product diversity of isolates were analyzed, including screening for genes encoding polyketide synthases (PKS) and nonribosomal peptide synthetase (NRPS), and 16S rRNA gene restriction fragment length polymorphism (RFLP). PKS and NRPS sequences were detected in more than half of the isolates and the different "PKS-I-PKS-II-NRPS" combinations in different isolates belonging to the same species indicated a potential natural product diversity and divergent genetic evolution. The phylogenetic analysis based on 16S rRNA gene sequencing showed that the isolates belonged to genera Streptomyces, Cellulosimicrobium, and Nocardiopsis. The majority of the strains tested belonged to the genus Streptomyces and one of them may be a new species. To our knowledge, this is the first report of a bacterium classified as Cellulosimicrobium sp. isolated from a marine sponge.