题目: Strepsesquitriol, a Rearranged Zizaane-Type Sesquiterpenoid from the Deep-Sea-Derived Actinomycete Streptomyces sp. SCSIO 10355 

作者: Xianwen Yang, Kun Peng, Zhong Liu, Gaiyun Zhang, Jie Li, Ning Wang,Andre Steinmetz, and Yonghong Liu* 

刊物: Journal of Natural Products,（IF=3.285，III区）

刊号: 2013,76:2360−2363 

摘要: Strepsesquitriol, a new caged sesquiterpene, was isolated from Streptomyces sp. SCSIO 10355. Its absolute structure was established as (1R,2R,4S,5S,8S,10S)-4,9,9,10-tetramethyl-2,5,10-trihydroxytricyclo[6.2.1.0(1,5)]undecane by NMR analysis and a theoretical optical rotation derived from quantum-chemical calculations. It showed moderate inhibitory activity against lipopolysaccharide-induced TNFα production in RAW264.7 macrophages.