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刘永宏研究团队在《Journal of Natural Products 》发表文章

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时间:2013-12-11  作者:LMB  来源:文本大小:【 |  | 】  【打印

题目: Strepsesquitriol, a Rearranged Zizaane-Type Sesquiterpenoid from the Deep-Sea-Derived Actinomycete Streptomyces sp. SCSIO 10355 

作者: Xianwen Yang, Kun Peng, Zhong Liu, Gaiyun Zhang, Jie Li, Ning Wang,Andre Steinmetz, and Yonghong Liu* 

刊物Journal of Natural Products,IF=3.285III区)

刊号: 2013,76:2360−2363 

摘要: Strepsesquitriol, a new caged sesquiterpene, was isolated from Streptomyces sp. SCSIO 10355. Its absolute structure was established as (1R,2R,4S,5S,8S,10S)-4,9,9,10-tetramethyl-2,5,10-trihydroxytricyclo[6.2.1.0(1,5)]undecane by NMR analysis and a theoretical optical rotation derived from quantum-chemical calculations. It showed moderate inhibitory activity against lipopolysaccharide-induced TNFα production in RAW264.7 macrophages. 

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