题目: Nutritional and Chemical Composition and Antiviral Activity of Cultivated Seaweed Sargassum naozhouense Tseng et Lu. 

作者: Yan Peng, Enyi Xie, Kai Zheng, Mangaladoss Fredimoses, Xianwen Yang, Xuefeng Zhou, Yifei Wang, Bin Yang, Xiupin Lin, Juan Liu, Yonghong Liu* 

刊物: Marine Drugs,（IF=3.973，II区）

刊号: 2013,11:20-32 

摘要: Sargassum naozhouense is a brown seaweed used in folk medicine and applied for thousands of years in Zhanjiang, Guangdong province, China. This study is the first time to investigate its chemical composition and antiviral activity. On the dry weight basis, this seaweed was constituted of ca. 35.18% ash, 11.20% protein, 1.06% lipid and 47.73% total carbohydrate, and the main carbohydrate was water-soluble polysaccharide. The protein analysis indicated the presence of essential amino acids, which accounted for 36.35% of the protein. The most abundant fatty acids were C14:0, C16:0, C18:1 and C20:4. The ash fraction analysis indicated that essential minerals and trace elements, such as Fe, Zn and Cu, were present in the seaweed. IR analysis revealed that polysaccharides from cultivated S. naozhouense may be alginates and fucoidan. The polysaccharides possessed strong antiviral activity against HSV-1 in vitro with EC(50) of 8.92 μg/mL. These results demonstrated cultivated S. naozhouense has a potential for its use in functional foods and antiviral new drugs. 

题目: New Sinularianin Sesquiterpenes from Soft Coral Sinularia sp. 

作者: Bin Yang, Shengrong Liao, Xiuping Lin, Junfeng Wang, Juan Liu, Xuefeng Zhou, Xianwen Yang, Yonghong Liu*  

刊物: Marine Drugs,（IF=3.973，II区）

刊号: 2013,11:4741-4750 

摘要: Four new sesquiterpenes, sinularianins C-F (3-6), together with known sinularianins A (1) and B (2) were identified from a South China Sea soft coral Sinularia sp. Compounds 1-6 were evaluated for inhibition of NF-κB activation using the cell-based HEK293 NF-κB luciferase reporter gene assay. Compounds 1 and 4 were exhibited a potent effect with inhibitory rates of 41.3% and 43.0% at the concentration of 10 µg/mL, respectively.