题目: Three new polyketides from marine-derived fungus Penicillium citrinum SCSGAF 0167 fungus Penicillium citrinum Three new polyketides from marine marinederived fungus Penicillium citrinumSCSGAF 0167

作者:  Yulin Sun, Xiaoyong Zhang, zhihui Zheng, Xinya Xu, Shuhua Qi*

名称：Natural Product Research, (IF=1.031, IV区)

刊号:  2014,28(4):239-244

摘要: Three new polyketides penicitrinol G (1), penicitrinol H (2) and 2,11-dihydroxy-1-methoxycarbonyl-9-carboxylxanthone (3) together with one known cathepsin B inhibitor chrysophanol (4) were isolated from a culture broth of marine-derived fungus Penicillium citrinum SCSGAF 0167. Their structures were determined by spectroscopic methods. Compound 4 exhibited inhibitory activity against cathepsin B with IC50 value of 1.7mM.