题目: Comparative contribution of trophic transfer and biotransformation on arsenobetaine bioaccumulation in two marine fish

作者: Wei Zhang, Zhiqiang Guo,Yanyan Zhou,Lizhao Chen,Li Zhang*

刊物: Aquatic Toxicology

年卷期页: 2016,179:65-71

摘要: tMarine fish can accumulate high arsenic (As) concentrations, with arsenobetaine (AsB) as the majorspecies in the body. However, whether the high AsB accumulation in fish occurs mainly through trophictransfer from diet or biotransformation in the fish body remains unclear. This study investigated thetrophic transfer and biotransformation of As in two marine fish (seabream Acanthopagrus schlegeli andgrunt Terapon jarbua) fed artificial and clam diets for 28 d. The different diets contained different pro-portions of inorganic [As(III) and As(V)] and organic [methylarsenate (MMA), dimethylarsenate (DMA),and AsB] As compounds. Positive correlations were observed between the accumulated As concentra-tions and AsB concentrations in both fish, suggesting that AsB contributed to the accumulation of totalAs in marine fish. Based on the calculated total input of AsB and detected AsB concentrations in themuscle of the seabream and grunt, the ingested amounts of AsB accounted for 0.1–0.3%, 8.1–14.4% ofdetected AsB concentrations, respectively, in the muscle of seabream and grunt fish species, suggestingthat AsB was mainly biotransformed versus trophically transferred in these marine fish. In summary, thisstudy demonstrates that marine fish prefer to biotransform inorganic As forms into AsB, resulting in highbioaccumulation of total As.