张黎研究员

（海洋重金属生态毒理学学科组责任研究员 zhangli @scsio.ac.cn）

研究兴趣与领域

1. 海洋生物对重金属的累积、转化与传递作用

2. 海洋鱼类对重金属等污染物的生理生态学响应

3. 重金属在海洋生态系统中的生物累积与生物地球化学 

代表性工作简介

围绕海洋生物和海洋环境的独特性，将生理实验、化学分析与数学模型相结合，解析海洋生态系统中重金属的生物富集、生物转化、食物链传递与毒理效应。阐释海洋鱼类累积重金属的生理生态特征；基于这些特征发展了用于模拟预测海洋鱼类富集重金属的生物动力学模型；解析了海洋生物对砷的生物转化过程，揭示了砷在海洋生物中的高累积和生物放大机制；发展了的重金属亚细胞分布决定理论，用于揭示重金属在海洋食物链中的传递规律。

学习经历

2003：厦门大学生物系，学士

2007：香港科技大学生物系，博士

工作经历

2007-2011： 加拿大麦克马斯特，博士后

2011-至今：中国科学院南海海洋研究所，责任研究员 

获奖与荣誉

1. 国家优秀青年科学基金获得者（2020）

2. 广东特支计划“百千万工程青年拔尖人才”（2014）

学术兼职

1. 中国动物学会动物生理生态学分会委员会委员（2018-2022）

2. 中国环境科学学会海洋生态安全专业委员会委员（2019-2023）

3.《水生生物学报》编委（2019-至今）

4. Environmental toxicology and Chemistry编委（Editorial Board）（2016-至今）

代表性学术成果

论文发表：

26. Yang Liu, Peng Zhang, Sen Du, Zhuoru Lin, Yanyan Zhou, Lizhao Chen, Rencheng Yu *, Li Zhang* Occurrence and distribution of lipophilic phycotoxins in a subtropical bay of the South China Sea. Chemosphere 2019, 243, 125-325

25. Lizhao Chen, Dongdong Song, Wei Zhang, Canchuan Zhang, Li Zhang* The dynamic changes of arsenic bioaccumulation and antioxidant responses in the marine medaka Oryzias melastigma during chronic exposure. Aquatic Toxicology 2019, 212, 110–119

24. Yang Liu, Peng Zhang, Sen Du, Zhuoru Lin, Yanyan Zhou, Lizhao Chen, Rencheng Yu *, Li Zhang* Sediment as a Potential Pool for Lipophilic Marine Phycotoxins with the Case Study of Daya Bay of China. Marine Drugs 2019, 17, 623

23. Zhiqiang Guo+, Zhixin Ni+, Hengzhen Ye, Juan Xiao, Lizhao Chen, Iain Greend, Li Zhang* Simultaneous uptake of Cd from sediment, water and diet in a demersal marine goby Mugilogobius chulae. Journal of Hazardous Materials 2019, 364, 143–150

22. Yun Wu, Yue Yuan, Hezhong Yuan, Wei Zhang, Li Zhang* Predicting cadmium toxicity with the kinetics of phytochelatin induction in a marine diatom. Aquatic Toxicology 2019, 207, 101–109

21. Wei Zhang, Zhiqiang Guo, Yun Wu, Yanlong Qiao, Li Zhang* Arsenic bioaccumulation and biotransformation in clams (Asaphis violascens) exposed to inorganic arsenic: effects of species and concentrations. Bulletin of Environmental Contamination and Toxicology 2019, 103, 114-119

20. Zhiqiang Guo, Hengzhen Ye, Juan Xiao, Christer Hogstrand, and Li Zhang* Biokinetic modeling of Cd bioaccumulation from water, diet and sediment in a marine benthic goby: a triple stable isotope tracing technique. Environmental Science and Technology. 2018,52,8429-8437

19. Wei Zhang, Zhiqiang Guo, Dongdong Song, Sen Du, Li Zhang* Arsenic speciation in wild marine organisms and a health risk assessment in a subtropical bay of China.. Science of the Total Environment 2018,626,621-629

18. Lizhao Chen+, Wei Zhang+, Zhiqiang Guo, Li Zhang* Effects of acclimation on arsenic bioaccumulation and biotransformation in freshwater medaka Oryzias mekongensis after chronic arsenic exposure. Environmental Pollution 2018,238,17-25

17. Yanyan Zhou, Fangsan Wei, Wei Zhang, Zhiqiang Guo, Li Zhang* Copper bioaccumulation and biokinetic modeling in marine herbivorous fish Siganus oramin. Aquatic Toxicology 2018,196,61-69

16. Limei Zhu, Na Gao, Ruifang Wang, Li Zhang* Proteomic and metabolomic analysis of marine medaka (Oryzias melastigma) after acute ammonia exposure. Ecotoxicology 2018,27,267-277

15. Gao N, Zhu L, Guo Z, Yi M*, Zhang L*, 2017. Effects of chronic ammonia exposure on ammonia metabolism and excretion in marine medaka Oryzias melastigma. Fish and Shellfish Immunology 65: 226-234.

14. Guo Z, Gao N, Wu Y, Zhang L*,2017. The simultaneous uptake of dietary and waterborne Cd in gastrointestinal tracts of marine yellowstripe goby Mugilogobius chulae. Environmental Pollution 223: 31-41.

13. Zhou Y, Zhang W, Guo Z, Zhang L*, 2017. Effects of salinity and copper co-exposure on copper bioaccumulation in marine rabbitfish Siganus oramin. Chemosphere 168: 491–500.

12. Wu Y, Guo Z, Zhang W, Tan Q, Zhang L*, Ge X, Chen M, 2016. Quantitative relationship between cadmium uptake and the kinetics of phytochelatin induction by cadmium in a marine diatom. Scietific Reports 6: 35935.

11. Zhang W, Guo Z, Zhou Y, Chen L, Zhang L*, 2016. Comparative contribution of trophic transfer and biotransformation on arsenobetaine bioaccumulation in two marine fish. Aquatic Toxicology 179: 65-71.

10. Jia P, Jia K, Chen L, Le Y, Jin Y, Zhang J, Zhu L, Zhang L*, Yi M*, 2016. Identification and characterization of the melanoma differentiation - associated gene 5 in sea perch, Lateolabrax japonicus. Dev Comp Immunol 61:161-168.

9. Zhang W, Wang WX, Zhang L*, 2016. Comparison of bioavailability and biotransformation of inorganic and organic arsenic to two marine fish. Environ Sci Technol 50: 2413-2423.

8. Zhang W, Chen L, Zhou Y, Wu Y, Zhang L*, 2016. Biotransformation of inorganic arsenic in a marine herbivorous fish Siganus fuscescens after dietborne exposure. Chemosphere 147: 297-304.

7. Guo Z, Zhang W, Du S, Zhou Y, Gao N, Zhang L*, Green I, 2016. Feeding reduces waterborne Cu bioaccumulation in a marine rabbitfish Siganus oramin. Environ Pollut 208: 580-589.

6. Guo Z, Zhang W, Du S, Green I, Tan Q, Zhang L*, 2016. Developmental patterns of copper bioaccumulation in a marine fish model Oryzias melastigma. Aquat Toxicol 170: 216-222.

5. Guo Z, Zhang W, Zhou Y, Gao N, Zhang L*, 2015. Feeding ratio and frequency affects cadmium bioaccumulation in black sea bream Acanthopagrus schlegeli. Aquacul Environ Inter 7: 135-145.

4. Zhang L, Nawata CM, De Boeck G, Wood, CM*, 2015. Rh protein expression in branchial neuroepithelial cells, and the role of ammonia in ventilatory control in fish. Comp Biochem Physiol A 186: 39-51.

3. Zhang W, Guo Z, Zhou Y, Liu H, Zhang L*, 2015. Biotransformation and detoxification of inorganic arsenic in Bombay oyster Saccostrea cucullata. Aquat Toxicol 158: 33-40.

2. Zhang W, Wang WX, Zhang L*, 2013. Arsenic speciation and spatial and interspecies differences of metal concentrations in mollusks and crustaceans from a South China estuary. Ecotoxicology 22: 671-682.

1. Zhang L*, Nawata CM, Wood CM, 2013. Sensitivity of ventilation and brain metabolism to ammonia exposure in rainbow trout, Oncorhynchus mykiss. J Exp Biol 216: 4025-4037.

学科组建设

责任研究员：张黎

助理研究员：周岩岩、柳阳

特别研究助理：陈李招、林先智

行政人员：范红玉

博士研究生：宋冬冬（2016）、杜森（2017）、张鹏（2018）、章灿川（2019）

硕士研究生：马群欢（2018）、刘天睿（2019）

已培养博士研究生4名；硕士研究生6名