漆淑华研究员

（海洋天然药物化学与化学生态学学科组责任研究员shuhuaqi@scsio.ac.cn）

研究兴趣与领域

主要从事海洋天然药物化学与化学生态学研究。

代表性成果简介

主要从事海洋动植物和海洋微生物的次生代谢产物研究，共分离鉴定了1500多个单体化合物，包括400多个新化合物，发现了一批抗病毒、抗肿瘤、抗生物膜形成、调节酶活力等活性化合物，探究了部分活性显著化合物的构效关系和作用机制，在抗病毒、抗肿瘤、酶抑制剂等方面发现10种新药先导化合物。

学习经历

2000-2003：中国科学院昆明植物研究所植物化学国家重点实验室，博士

工作经历

2003-至今：中国科学院南海海洋研究所，责任研究员

2005-2007：香港科技大学生物系，博士后

2009：加拿大不列颠哥伦比亚大学微生物系，高级访问学者

获奖与荣誉

1. 海南省科技进步特等奖（2004，第四）

2. 国家科技进步二等奖（2007，第五）

学术兼职

1. 中国微生物学会海洋微生物学专业委员会委员（2016-2020）

2. 广东省药学会药物化学专业委员会委员（2016-2020）

3. 广东省药学会天然药物化学专业委员会委员（2016-2020）

4. 广东省生物医学生物工程学会生物工程分会委员（2016-2020）

5. 中国药学会海洋药物专业委员会委员（2019-2024）

代表性学术成果

论文发表

70. Muhammad Amin, Xiao-Yong Zhang, Xin-Ya Xu, Shu-Hua Qi*. New citrinin derivatives from the deep-sea-derived fungus Cladosporium sp. SCSIO z015. Natural Product Research. 2019, 10.1080/14786419.2018.1556266

69. Dongyan Pan, Xuexia Zhang, Haizhou Zheng, Zhihui Zheng, Xuhua Nong, Xiao Liang, Xuan Ma and Shuhua Qi*. Novel anthraquinone derivatives as inhibitors of protein tyrosine phosphatases and indoleamine 2,3-dioxygenase 1 from the deep-sea derived fungus Alternaria tenuissima DFFSCS013. Organic Chemistry Frontiers. 2019, 6, 3252-3258.

68. Xiao Liang, Xuelian Zhang, Xinhua Lu, Zhihui Zheng, Xuan Ma, Shuhua Qi*. Diketopiperazine-Type Alkaloids from a Deep-Sea-Derived Aspergillus puniceus Fungus and Their Effects on Liver X Receptor α. Journal of  Natural  Products. 2019, 82, 1558？1564

67. Xuan Ma, Xiao Liang, Zhong-Hui Huang, Shu-Hua Qi*. New alkaloids and isocoumarins from the marine gorgonian-derived fungus Aspergillus sp. SCSIO 41501. Natural Product Research. 2019, https://doi.org/10.1080/14786419. 2019.1569660

66. Muhammad Amin, Xiao Liang, Xuan Ma, Jun-De Dong, Shu-Hua Qi*. New pyrone and cyclopentenone derivatives from marine-derived fungus Aspergillus sydowii SCSIO 00305. Natural Product Research. 2019, https://doi.org/ 10.1080/14786419.2019.1629919.

65. S.A.H.K. Dasanayaka, Xu-Hua Nong, Xiao Liang, Jian-Qiu Liang, Muhammad Amin, Shu-Hua Qi*. New dibenzodioxocinone and pyran-3,5-dione derivatives from the deep-sea-derived fungus Penicillium canescens SCSIO z053. Jounal of Asian Natural  Products Research. 2019, doi.org/10.1080/10286020.2019.1575819

64. Xiao Liang, Zhong-Hui Huang, Xuan Ma, and Shu-Hua Qi*. Unstable Tetramic Acid Derivatives from the Deep-Sea-Derived Fungus Cladosporium sphaerospermum EIODSF 008. Marine Drugs. 2018,16,448

63. Jie Wang, Xu-Hua Nong, Muhammad Amin, Shu-Hua Qi*. Hygrocin C from marine-derived Streptomyces sp. SCSGAA 0027 inhibits biofilm formation in Bacillus amyloliquefaciens SCSGAB0082 isolated from South China Sea gorgonian. Applied Microbiology and Biotechnology. 2018,102(3):1417-1427

62. Zhong-hui Huang, Xu-hua Nong, Xiao Liang, Shu-hua Qi*. New tetramic acid  derivatives from the deep-sea-derived fungus Cladosporium sp. SCSIO z0025. Tetrahedron.  2018,74,2620-262

61. Xiao-Yong Zhang, Muhammad Amin, Xin-Ya Xu, Shu-Hua Qi*. Antifouling Potentials and Metabolite Profiles of Two Marine-derived Fungal Isolates. Natural Product Communications. 2018,13:423-426

60. Xiao Liang, Xu-Hua Nong, Zhong-Hui Huang, Shu-Hua Qi*. Antifungal and antiviral cyclic peptides from the deep-sea-derived fungus Simplicillium obclavatum EIODSF 020. J. Agric. Food Chem. 2017, 65, 5114–5121.

59. Xinya Xu, Xiaoyong Zhang, Xuhua Nong, Jie Wang, Shu-Hua Qi*. Brevianamides and mycophenolic acid derivatives from the deep-sea-derived fungus Penicillium brevicompactum DFFSCS025. Marine Drugs. 2017, 15, 43.

58. Shu-Hua Qi*, Xuan Ma. Antifouling compounds from marine invertebrates. Marine Drugs. 2017, 15, 263.

57. Jie Wang, Xu-Hua Nong, Muhammad Amin, Shu-Hua Qi*. Hygrocin C frommarine-derived Streptomyces sp. SCSGAA 0027 inhibits biofilm formation in Bacillus amyloliquefaciens SCSGAB0082 isolated from South China Sea gorgonian. Appl. Microbiol. Biotechnol. 2017, DOI: https://doi.org/10.1007/s00253-017-8672-z.

56. Jie Wang, Qi-Feng Yao, Muhammad Amin, Xu-Hua Nong, Xiao-Yong Zhang, Shu-Hua Qi*. Penicillenols from a deep-sea fungus Aspergillus restrictus inhibit Candida albicans biofilm formation and hyphal growth. J. Antibiot. 2017, 70, 763-770.

55. Jie Wang, Xu-Hua Nong, Xiao-Yong Zhang, Xin-Ya Xu, Muhammad Amin, Shu-Hua Qi*. Screening of anti-biofilm compounds from marine-derived fungi and the effects of secalonic acid D on Staphylococcus aureus biofilm. Anti-HSV-1, antioxidant and antifouling phenolic compounds from the deep-sea-derived fungus Aspergillus versicolor SCSIO 41502. J. Microbiol. Biotechnol. 2017, 27, 1078-1089

54. Zhonghui Huang, Xuhua Nong, Zhe Ren, Jie Wang, Xiaoyong Zhang, Shu-Hua Qi*. Screening of anti-biofilm compounds from marine-derived fungi and the effects of secalonic acid D on Staphylococcus aureus biofilm. Bioorg. Med. Chem. Lett. 2017, 27, 787-791.

53. Xuan Ma, Xu-Hua Nong, Zhe Ren, Jie Wang, Xiao Liang, Shu-Hua Qi*. Antiviral peptides from marine gorgonian-derived fungus Aspergillus sp. SCSIO 41501. Tetrahedron Lett. 2017, 58, 1151-1155.

52. Jie Bao, Jie Wang, Xiao-Yong Zhang, Xu-Hua Nong, Shu-Hua Qi*. New Furanone Derivatives and Alkaloids from the Co-Culture of Marine-Derived Fungi Aspergillus sclerotiorum and Penicillium citrinum. Chem. Biodiversity. 2017, 14 e1600327.

51. Jie Wang, Qiao-Li Wang, Xu-Hua Nong, Xiao-Yong Zhang, Xin-Ya Xu, Shu-Hua Qi*, Yi-Fei Wang. Oxalicumone A, a new dihydrothiophene-condensed sulfur chromone induces apoptosis in leukemia cells through endoplasmic reticulum stress pathway. Eur J Pharmacol. 2016, 783, 47–55.

50. Xiao Liang, Xiao-Yong Zhang, Xu-Hua Nong, Jie Wang, Zhong-Hui Huang, Shu-Hua Qi^*. Eight linear peptides from the deep-sea-derived fungus Simplicillium obclavatum EIODSF 020. Tetrahedron, 2016, 72, 3092-3097.

49. Xu-Hua Nong, Xiao-Yong Zhang, Xin-Ya Xu, Jie Wang, Shu-Hua Qi^*. Nahuoic Acids B-E, Polyhydroxy Polyketides from the Marine-derived Streptomyces sp. SCSGAA 0027. J Nat Prod., 2016, 79, 141-148.

48. Yu-Lin Sun, Xiao-Yong Zhang, Xu-Hua Nong, Xin-Ya Xu, Shu-Hua Qi^*. New Antifouling Macrodiolides from the Deep-Sea-Derived Fungus Trichobotrys effuse DFFSCS021. Tetrahedron Letter, 2016, 57, 366-370.

47. Yun-Lin Sun, Jie Wang, Yi-Fei Wang, Xiao-Yong Zhang, Xu-Hua Nong, Mao-Yun Chen, Xin-Ya Xu, Shu-Hua Qi*. Cytotoxic and Antiviral Tetramic Acid Derivatives from the Deep-Sea-Derived Fungus Trichobotrys effuse DFFSCS021. Tetrahedron, 2015, 71(49), 9328-9332.

46. Xin-Ya Xu, Xiao-Yong Zhang, Xu-Hua Nong, Xiao-Yi Wei, Shu-Hua Qi*. Oxindole alkaloids from the fungus Penicillium commune DFFSCS026 isolated from deep-sea-derived sediments. Tetrahedron, 2015, 71(4), 610-615.

45. Xu-Hua Nong, Xiao-Yong Zhang, Xin-Ya Xu, Shu-Hua Qi*. Antifouling Compounds from the Marine-Derived Fungus Aspergillus terreus SCSGAF0162. Natural Product Communications. 2015, 10(6), 1033-1034.

44. Qifeng Yao, Jie Wang, Xiaoyong Zhang, Xuhua Nong, Xinya Xu, Shuhua Qi*. Cytotoxic Polyketides from the Deep-Sea-Derived Fungus Engyodontium album DFFSCS021. marine drugs. 2014,12(12):5902-5915

43. Xuhua Nong, Yifei Wang, Xiaoyong Zhang, Muping Zhou, Xinya Xu, Shuhua Qi*. Territrem and Butyrolactone Derivatives from a Marine-Derived Fungus Aspergillus Terreus. marine drugs. 2014,12(12):6113-6124

42. Xiaoyong Zhang, Xinya Xu, Jiang Peng, Chunfeng Ma, Xuhua Nong, Jie Bao, Guangzhao Zhang, Shuhua Qi*. Antifouling potentials of eight deep？sea？derived fungi from the South China Sea. J Ind Microbiol Biotechnol. 2014,41:741-748

41. Xiaoyong Zhang, Guiling Tang, Xinya Xu, Xuhua Nong, ShuHua Qi*. Insights into Deep-Sea Sediment Fungal Communities from the East Indian Ocean Using Targeted Environmental Sequencing Combined with Traditional Cultivation. PLOS One. 2014,9(10)e109118

40. Jiejie Dong, Jie Bao, Xiaoyong Zhang, Xinya Xu, Xuhua Nong, Shuhua Qi*. Alkaloids and citrinins from marine-derived fungus Nigrospora oryzae SCSGAF 0111. Tetrahedron Letters. 2014,55:2749-2753

39. Jie Bao, Jinfeng Luo, Xiaochu Qin, Xinya Xu, Xiaoyong Zhang, Zhengchao Tu, Shuhua Qi*. Dihydrothiophene-condensed chromones from a marine-derived fungus Penicillium oxalicum and their structure–bioactivity relationship. Bioorganic & Medicinal Chemistry Letters. 2014,24:2433-2436

38. Jie Bao, Xiaoyong Zhang, Jiejie Dong, Xinya Xu, Xuhua Nong, Shuhua Qi*. Cyclopentane-condensed Chromones from Marine-derived Fungus Penicillium oxalicum. Bioorganic & Medicinal Chemistry Letters. 2014,43:837-839

37. Yulin Sun, Xiaoyong Zhang, zhihui Zheng, Xinya Xu, Shuhua Qi*. Three new polyketides from marine-derived fungus Penicillium citrinum SCSGAF 0167 fungus Penicillium citrinum. Natural Product Research. 2014,28(4):239-244

36. Xuhua Nong, Xiaoyong Zhang, Xinya Xu, Yunlin Sun, Shuhua Qi*. Alkaloids from Xylariaceae sp., a Marine-derived Fungus. Natural Product Communications. 2014,9(4):467-468

35. Jie-Jie Dong, Jie Bao, Xiao-Yong Zhang, Xin-Ya Xu, Xu-Hua Nong, Shu-Hua Qi*. Alkaloids and citrinins from marine-derived fungus Nigrospora oryzae SCSGAF 0111. Tetrahedron Letters, 2014, 55, 2749–2753.

34. Jie Bao, Jin-Feng Luo, Xiao-Chu Qin, Xin-Ya Xu, Xiao-Yong Zhang, Zheng-Chao Tu, Shu-Hua Qi*. Dihydrothiophene-condensed chromones from a marine-derived fungus Penicillium oxalicum and their structure–bioactivity relationship. Bioorganic Medicinal Chemistry Letters, 2014, http://dx.doi.org/10.1016/j.bmcl.2014.04.046.

33. Xiao？Yong Zhang · Xin？Ya Xu · Jiang Peng ·Chun？Feng Ma · Xu？Hua Nong · Jie Bao ·Guang？Zhao Zhang · Shu？Hua Qi*. Antifouling potentials of eight deep？sea？derived fungi from the South China Sea. J Ind Microbiol Biotechnol. 2014, 41:741–748

32. Xuhua Nong, Zhihui Zheng, Xiaoyong Zhang, Xinhua Lu, Shuhua Qi*. Polyketides from a marine-derived Funus Xylariaceae sp. Marine Drugs 2013,11(5):1718-1727

31. Xiaoyong Zhang, Jie Bao, Juan Zhong, Xinya Xu, Shuhua Qi*. Enhanced production of a novel cytotoxic chromone oxalicumone A by marine-derived mutant penicillium oxalicum SCSIO 24-2. Applied Microbiology and Biotechnology 2013,97(22),9657-9663

30. Xinya Xu, Fei He, Xiaoyong Zhang, Jie Bao, Shuhua Qi*. New mycotoxins from marine-derived fungus Aspergillus sp. SCSGAF0093. Food and Chemical Toxicology 2013,53:46-51

29. Jiang Peng, Xiaoyong Zhang, Zhengchao Tu, Xinya Xu, Shuhua Qi*. Alkaloids from the Deep-Sea-Derived Fungus Aspergillus westerdijkiae DFFSCS013. Journal of Natural Products 2013,76(5):983-987

28. Fei He, Jie Bao, Xiaoyong Zhang, Zhengchao Tu, Yiming Shi, Shuhua Qi*. Asperterrestide A, a Cytotoxic Cyclic Tetrapeptide from the Marine-Derived Fungus Aspergillus terreus SCSGAF0162. Journal of Natural Products 2013,76(6):1182-1186

27. Jie Bao, Xiaoyong Zhang, Xinya Xu, Fei He, Xuhua Nong, Shuhua Qi*. New cyclic tetrapeptides and asteltoxins from gorgonian-derived fungus Aspergillus sp. SCSGAF 0076. Tetrahedron 2013,69(9):2113-2117

26. Xiaoyong Zhang, Jie Bao, Fei He, Xinya Xu, Shuhua Qi*. Diversity and antibacterial activity of culturable actinobacteria isolated from five species of the South China Sea gorgonian corals. World J Microbiol Biotechnol 2013,29(6):1107-1116

25. Jie Bao, Yulin Sun, Xiaoyong Zhang, Zhuang Han, Fei He, Haichun Gao, Peiyuan Qian, Shuhua Qi*. Antifouling and antibacterial polyketides from marine gorgonian-associated fungus Penicillium oxalicum SCSGAF 0023. Journal of Antibiotics 2013,66(4):219-223

24. Xiaoyong Zhang, Yun Zhang, Xinya Xu, Shuhua Qi*. Diverse deep-sea fungi from the South China Sea and their antimicrobial activity. Current Microbiology 2013,67(5):525-530

23. Jiang Peng, Xiaoyong Zhang, Xinya Xu, Fei He, Shuhua Qi*. Diversity and Chemical Defense Role of Culturable Non-actinobacterial Bacteria Isolated from the South China Sea Gorgonians. Journal of Microbiology and Biotechnology 2013,23(4):437-443

22. Jie Bao, Xin-Ya Xu, Xiao-Yong Zhang, Shu-Hua Qi*. A new macrolide from a marine-derived fungus Asperillus sp.. Natural Product Communications 2013,8(8):1127-1128

21. Xinya Xu, Xiaoyong Zhang, Fei He, Jiang Peng, Xuhua Nong, Shuhua Qi*. Two New Compounds from Gorgonian-associated Fungus Aspergillus sp. Natural Product Communications 2013,8(8):1069-1070

20. Fei He, Zhuang Han, Jiang Peng, Peiyuan Qian, Shuhua Qi*. Antifouling Indole Alkaloids from Two Marine Derived Fungi. Natural Product Communications 2013,8(3):329-332

19. Xiao-Yong Zhang, Jie Bao, Guang-Hua, Wang, Fei He, Xin-Ya Xu, Shu-Hua QI*. Diversity and antimicrobial activity of culturable fungi isolated from six species of the South China Sea gorgonian corals. Microbial Ecology. 2012, 64, 617-627

18. Fei He, Zhong Liu, Jin Yang, Peng Fu, Jiang Peng, Wei-Min Zhu, Shu-Hua Qi*. A Novel Antifouling Alkaloid from Halotolerant Fungus Penicillium sp. OUCMDZ-776. Tetrahedron Letters. 2012, 53, 2280-2283

17. Li-Si Huang, Fei He, Hui Huang, Xiao-Yong Zhang, Shu-Hua Qi*. Carbamate Derivatives and Sesquiterpenoids from the South China Sea Gorgonian Melitodes squamata. Beilstein Journal of Organic Chemistry. 2012, 8, 170-176

16. Xiaoyong Zhang, Yulin Sun, Jie Bao, Fei He, Xinya Xu, Shuhua Qi*. Phylogenetic survey and antimicrobial activity of culturable microorganisms associated with the South China Sea black coral Antipathes dichotoma. FEMS Microbiology Letters. 2012, 336(2):122-130

15. Xinya Xu, Fei He, Xiaoyong Zhang, Jie Bao, Shuhua Qi*. New mycotoxins from marine-derived fungus Aspergillus sp. SCSGAF0093. Food and Chemical Toxicology. 2013, 53: 46–51

14. Yu-Lin Sun, Fei He, Kai-Sheng Liu, Xiao-Yong Zhang,Jie Bao, Yi-Fei Wang, Xu-Hua Nong, Xin-Ya Xu, Shu-Hua Qi*. Cytotoxic sulfur-containing chromones from marine gorgonian-associated fungus Penicillium oxalicum SCSGAF 0023. Planta Medica. 2012; 78(18): 1957-1961

13. Fei He, Yu-Lin Sun, Kai-Sheng Liu, Xiao-Yong Zhang, Pei-Yuan Qian, Yi-Fei Wang, and Shu-Hua Qi*. Indole Alkaloids from Marine-Derived Fungi Aspergillus sp. SCSIO 00305. The Journal of Antibiotics. 2012, 65, 109-111

12. Shu-Hua Qi, Fei He, Li-Si Huang, Jun-De Dong. Phytochemical and chemotaxonomic investigation of the South China Sea seagrass Thalassia hemprichii. Biochemical Systematics and Ecology. 2012, 43, 128-131

11. ChengHai Gao, Shen Li, Pei Yuan Qian, Yi Fei Wang, Shu Hua Qi*，Alkaloids and Sesquiterpenes from the South China Sea gorgonian Echinogorgia pseudossapo，Marine Drugs, 2011, 9:2479-2487

10. Ping Wang, shu-Hua Qi, Kai-Sheng Liu, Li-Si Huang, Fei He, and Yi-Fei Wang*,Steroids from the South China Sea Gorgonian Coral Muricella flexuosa.，Z.Naturforsch.2011,66(b): 635-640

9. Cheng-Hai Gao,Xin-Peng Tian, Shu-Hua Qi*, et al. Antibacterial and antilarval compounds from marine gorgonian-associated bacterium Bacillus amyloliquefaciens SCSIO 00856. The Journal of Antibiotics. 2010, 63: 191-193.

8. Shu-Hua Qi, Li Miao, Ying Xu, Si Zhang. Steroids and alkaloids from the gorgonian Isis minorbrachyblasta: Structures, cytotoxicity and antilarval activity. Helve. Chim. Acta. 2010, 93: 511-516.

7. Shu-Hua Qi, Si Zhang, Hui Huang. Four purine alkaloids from the South China Sea gorgonian Subergorgia suberosa. J. Nat. Prod. 2008, 71(4):716-718.

6. Shu-Hua Qi, Si Zhang, Yi-Fei Wang. Complete 1H and 13C NMR assignments of three new polyhydroxylated sterols from the South China Sea gorgonian Subergorgia suberosa. Magn.Res.Chem. 2007, 45(12): 1088-1091.

5. Shu-Hua Qi, Si Zhang, Bei-Yuan Qian, Zhi-Hui Xiao, Ming-Yi Li. Ten new antifouling briarane diterpenoids from the South China Sea gorgonian Junceella juncea. Tetrahedron 2006, 62: 9123-9130.

4. Shu-Hua Qi, Si Zhang, Xiang Li, Zhi-Hui Xiao. A New Cytotoxic Sesquiterpene-Alkaloid from the South China Sea gorgonian Subergorgia suberosa. J. Nat.Prod. 2005, 68: 1288 –1289

3. Shu-Hua Qi, Si Zhang, Zhi-Hui Xiao, Jian-She Huang. New Briaranes from the South China Sea Gorgonian Junceella juncea. J. Nat. Prod. 2004, 67(11): 1907-1910.

2. Shu-Hua Qi, Da-Gang Wu, Li Chen, Yun-Bao Ma, Xiao-Dong Luo. Insect Antifeedants from Munronia henryi: Structure of Munroniamide, J. Agric. Food Chem. 2003, 51: 6949-6952.

1. Shu-Hua Qi, Li Chen, Xiao-Dong Luo. Novel Tetranortriterpenoid Derivatives from Munronia henryi. Tetrahedron 2003, 59: 4193-4199.

授权专利

1. 西松烷型二萜，ZL200410027587.1，漆淑华，张偲

2. 灯心柳珊瑚皂苷，ZL200410027588.6，漆淑华，张偲，

3. 一种倍半萜侧扁软柳珊瑚酮及其制备方法和应用，ZL200510033704.X，漆淑华，张偲，李翔

4. 西松烷型二萜及其制备方法和用途，ZL200610035912.8，漆淑华，张偲

5. 一种新嘌呤类生物碱及其制备方法和应用，ZL200710029847.2，漆淑华，张偲

6. 一种多羟基开环甾醇及其制备方法和抗肿瘤用途，ZL200710031372.0，漆淑华，张偲

7. 一种咔唑类生物碱及其制备方法和应用，ZL200810030208.2, 漆淑华，张偲

8. 一种泰来草提取物及其制备方法和应用，ZL200810030161.X, 漆淑华

9. 一种柳珊瑚多羟基甾醇及其制备方法和应用，ZL200810220428.1，漆淑华，张偲

10. 一种大环内酯及其制备方法和抗菌用途，ZL200910194148.2,20，漆淑华

11. 一种硫酸化黄酮苷在制备抗单纯疱疹病毒药物中的应用，ZL201110041737.4，漆淑华

12. 一种螺环生物碱化合物及其制备方法和抗海洋生物污损方面的应用，ZL1110151198.x，漆淑华，贺飞

13. 一类环四肽化合物及其制备方法和在制备抗污损剂中的应用，ZL201210431886.6，漆淑华 鲍洁

14. 一株产表面活性素和伊枯草菌素A类化合物的甲基营养型芽孢杆菌及其应用，ZL 201210431946.4，漆淑华 张晓勇 彭江

15. 一类吲哚生物碱在制备抗海洋生物污损涂料中的应用，ZL 201210244723.7，漆淑华 贺飞

16. 一类环四肽化合物及其制备方法和在制备抗污损材料中的应用, ZL2012104318866,漆淑华 鲍洁

17. 一类苯并杂环生物碱在制备抗海洋生物污损涂料中的应用， ZL201310682038.7，漆淑华 张晓勇 徐新亚

18. 一类生物碱类化合物及其制备方法和在制备抗海洋生物污损涂料与抗肿瘤药物中的应用，ZL201310135149.6，漆淑华 张晓勇  彭江  徐新亚

19. 一类色酮类化合物及其制备方法和在制备抗肿瘤与酶抑制剂药物中的应用， ZL201310413815.8, 漆淑华  鲍洁

20. 一类丁烯酸内酯化合物在制备抗海洋生物污损涂料中的应用，专利号ZL201410583640.X, 漆淑华 农旭华 张晓勇 徐新亚

21. 两个色酮类化合物及其制备方法和在制备抗肿瘤药物中的应用，ZL201410706527.6, 漆淑华 姚期凤 王洁 张晓勇 农旭华 徐新亚

学科组建设

责任研究员：漆淑华

特别研究助理：梁潇

博士研究生：杨程霞（2017）、刘晓波（2019）、S ARACHCHILLAGE HARSHANIE KANCHANAMALA DASANAYAKA（2019）

硕士研究生：姚飞华（2017）、刘瑶（2018）、刘成梅（2019）、FIRMANSYAH KARIM （2019）

已培养博士研究生7名；硕士研究生8名