中国科学院青年创新促进会员 张辉贤副研究员(2019)
副标题:
张辉贤博士 副研究员
(海洋动物生理与分子生态学学科组 Zhanghuixian123@163.com)
研究领域
长期从事海洋动物(以海马为代表)的行为生态与进化研究,在国际上首次完成海马的全基因组测序,揭示海马形态调节、进化和遗传等特征,并对海马雄性育儿的繁殖机制进行系统研究,阐明繁殖补偿的调控机理;同时,首次鉴定七鳃鳗的ParaHox基因家族,阐明脊椎动物的进化特征。
代表性工作简介
在国际上首次完成海马的全基因组测序,揭示海马形态调节、进化和遗传等特征,并对海马雄性育儿的繁殖机制进行系统研究,阐明繁殖补偿的调控机理;同时,首次鉴定无颌鱼类的ParaHox基因家族,阐明脊椎动物的进化特征。
学习经历
2008.09- 2013.07:中山大学,生理学,博士(导师:林浩然院士)
2004.09- 2008.07:山西师范大学,生物科学,学士
工作经历
2013.07- 2017.12:中国科学院南海海洋研究所,助理研究员
2018.01-至今:中国科学院南海海洋研究所,副研究员
2015.09- 2016.09:新加坡科技研究局(A*STAR, IMCB),青年访问学者
2019.05-2019.06:日本上智大学,访问学者
获奖及荣誉
1. 2012年获得中山大学生命科学学院林浩然院士奖学金三等奖;
2. 2013年获得中山大学有害生物控制与资源利用国家重点实验室奖学金二等奖
3. 2017年入选广东省特支计划“科技创新青年拔尖人才
4. 2018年获得广州市珠江科技新星称号
5. 2019年入选中国科学院青年创新促进会
代表性成果
论文发表(第一或通讯作者)
10. Huixian Zhang, Lingzhen Chen, Bo Zhang, Qiang Lin*. Molecular identification of GnIH and its potential role in reproductive physiology and male pregnancy of the lined seahorse (Hippocampus erectus)【封面论文】. General and Comparative Endocrinology. 2019, 179: 196-202
9. Huixian Zhang, Bo Zhang, Geng Qin, Shuisheng Li, Qiang Lin*. The roles of the kisspeptin system in the reproductive physiology of the lined seahorse (Hippocampus erectus), an ovoviviparous fish with male pregnancy. Frontiers in Neuroscience. 2018,12:940
8. Huixian Zhang, Geng Qin, Jinhui Sun, Bo Zhang, Qiang Lin*. The evolution and functional characterization of lined seahorse (Hippocampus erectus) CCKs involved in fasting and thermal stress response. General and Comparative Endocrinology. 2018,255:56-63
7. Qiang Lin1*, Shaohua Fan1, Yanhong Zhang1, Meng Xu1, Huixian Zhang1, Yulan Yang1, Alison P. Lee, Joost M. Woltering, Vydianathan Ravi, Helen M. Gunter, Wei Luo, Zexia Gao, Zhi Wei Lim, Geng Qin, Ralf F. Schneider, Xin Wang, Peiwen Xiong, Gang Li, Kai Wang, Jiumeng Min, Chi Zhang, Ying Qiu, Jie Bai, Weiming He, Chao Bian, Xinhui Zhang, Dai Shan, Hongyue Qu, Ying Sun, Qiang Gao, Liangmin Huang, Qiong Shi*, Axel Meyer*, Byrappa Venkatesh*.The seahorse genome and the evolution of its specialized morphology. Nature, 2016, 540 (7633): 395-399. 【封面论文】
6. Huixian Zhang1, Vydianathan Ravi1, Boon-Hui Tay, Sumanty Tohari, Nisha E. Pillai, Aravind Prasad, Qiang Lin, Sydney Brenner*, Byrappa Venkatesh*. Lampreys, the jawless vertebrates, contain only two Parahox gene clusters. PNAS. 2017, 114 (34): 9146-9151.
5. Huixian Zhang, Geng Qin, Yanhong Zhang, Shuisheng Li, Qiang Lin*. The leptin system and its expression at different nutritional and pregnant stages in lined seahorse (Hippocampus erectus). Biology Open, 2016, 5 (10): 1508-1515. 【封面论文】
4. Huixian Zhang, Geng Qin, Jinhui Sun, Bo Zhang, Qiang Lin. The evolution and functional characterization of lined seahorse (Hippocampus erectus) CCKs involved in fasting and thermal stress response. General and Comparative Endocrinology. 2018, 255: 56-63.
3. Huixian Zhang, Yanhong Zhang, Geng Qin, Qiang Lin*. The complete mitochondrial genome sequence of the network pipefish (Corythoichthys flavofasciatus) and the analyses of phylogenetic relationship within the Syngnathidae species. Marine genomics, 2015, 19: 59-64.
2. Huixian Zhang, Yanhong Zhang, Qiang Lin*. Complete mitochondrial genome of the pacific seahorse Hippocampus ingens Girard, 1858 (Gasterosteiformes: Syngnathidae). Mitochondrial DNA, 2015, 26(5): 755-756.
1. Huixian Zhang, Huapu Chen, Yong Zhang, Shuisheng Li, Danqi Lu, Haifa Zhang, Zining Meng, Xiaochun Liu*, Haoran Lin*. Molecular cloning, characterization and expression profiles of multiple leptin genes and a leptin receptor gene in orange-spotted grouper (Epinephelus coioides). General and Comparative Endocrinology, 2013, 181: 295-305.
授权专利(第一发明人)
(1) 刘晓春,张辉贤,李水生,张勇,蒙子宁,林浩然. 斜带石斑鱼瘦素Leptin A蛋白表达纯化的方法及应用,ZL201410617687.3 (导师为第一发明人)
(2) 张辉贤,林强,张艳红,秦耿,罗伟,一种海马催产剂及其编码基因,ZL2016102114966
(3) 张辉贤,林强,秦耿,张博. 一种杂交海马及其亲本的鉴定引物和鉴定方法. 201710550638.6
其他成果
参与完成广东省科技成果鉴定“美国线纹海马引种驯化、人工繁育及健康养殖关键技术”(登记号:粤科成等(2)字【2015】0017)